Timeline 1 By andrealedia Period: 399 BCE to 300 Silk is introduced into the Eastern Roman Empire and the Edge of the Mediterranean. Period: 139 BCE to 126 BCE Zhang Qian travels to central Asia 1 CE Silk is first introduced into Rome 184 Yellow Turban Uprising 220 The Han Dynasty Collapsed Period: 284 to 305 The Reign of Diocletian 313 Edict of Milan Period: 313 to 337 The Reign of Constantine 325 The Council of Nicaea 476 The Western Roman Empire Collapses