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A Roman fleet arrived in Illyria to relieve a Macedonian siege of Abydos.
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Alexander was killed in a mutiny of the Legio XXII Primigenia at Mainz.
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A Roman army defeated a combined force of Etruscans, Boii and Senones near Lake Vadimo.
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Constantine the Great had a vision of the cross appearing over the sun at the Ponte Milvio with the words "in this sign, conquer." His forces defeated and killed Maxentius.
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The Sasanian shah Shapur II invaded Armenia and Mesopotamia.
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Julian defeated a vastly superior Alemanni force near Argentoratum, solidifying Roman control west of the Rhine.
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A combined Gothic-Alanic force decisively defeated the Roman army near Edirne. Valens was killed.
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His elder son Arcadius succeeded him as augustus in the eastern Byzantine Empire. The young Honorius became sole augustus in the Western Roman Empire under the regency of Magister militum Stilicho.
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A coalition of foreign tribes including the Vandals, Alans and Suebi invaded the Western Roman Empire across the Rhine.
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Rome was sacked by the Visigoths under their king Alaric I.
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Valentinian III was assassinated on orders of the senator Petronius Maximus.
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Zeno recaptured Constantinople and accepted Basiliscus's surrender. Odoacer conquered the Western Roman capital Ravenna, forced Romulus to abdicate and declared himself king of Italy.
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A Byzantine army dealt a decisive defeat to the Ostrogoths at Gualdo Tadino. The Ostrogoth king Totila was killed.