Rise of Christianity in the Roman Empire By Buffdaddy315 64 Great Fire of Rome .The fire started in the shops at the circus maximums that quickly turned into an inferno . 64 Jesus of Nazareth 64 Paul of Tarsus 66 Roman Rule of Israel (begins) 181 Perpetua 272 Constantine the Great 303 Great Persecution of 303 CE 312 Battle of Milvian Bridge 313 Edict of Milan 379 Emperor Theodosius