Fall of the Byzantine Emire By Matthew Beam 565 Byzantine Empire at its height. The empire was at its height 565. At that time it had the most land and money. Jan 1, 693 Muslims attack Constantinople. Jan 1, 721 Regains Asia MInor from Muslims. Jan 1, 1055 Loss of southern Italy to the Normans. Jan 1, 1075 Loss Syria to Muslims Jan 1, 1087 Byzantine defeats in Thrace. Jan 1, 1121 Reconquest of southwestern Asia Minor. Jan 1, 1202 Fourth Crusade is assembled at Venice. Jan 1, 1204 Fall of the Constantinople. Jan 1, 1453 Byzantine Empire at its fall. The fall of the Byzantine Empire.