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The East Roman Empire began to collapse around the 1000's.
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By 1071AD the Normans had taken over Southern Italy
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Emperor Alexius Comnenus became Emperor in 1081 asked the Christiams of Western Europe to help defend the Empire against the Turks.
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By the late 1300's Constantinpole and parts of Greece were all the remained of the East Roman Empire.
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The Empire ended when Ottoman Turks captured Constantinpole in 1453.