Timeline Assignment- BMT By leryannw 1736 Claudius Aymand performs the first successful appendectomy 1796 Edward Jenner develops a smallpox vaccination method 1849 Elizabeth Blackwell is the first woman to gain a medical degree in the United States. 1879 First vaccine for cholera. 1901 Karl Landsteiner discovers the existence of different human blood types 1921 Edward Mellanby discovers vitamin D and shows that its absence causes rickets 1933 Manfred Sakel discovers insulin shock therapy 1952 Cloning – Robert Briggs and Thomas King 1974 Liposuction – Giorgio Fischer 1981 Artificial skin – John F. Burke and Loannis V Yannas