Claudius Galenus, physiologist, proved that arteries contain blood and that arteries and veins are noticeably different.
BCE. Herophilus of Chalcedon
Herophilus of Chalcedon a Greek anatomist, discovers that arteries carry blood and are thicker than veins.
BCE. Aristotle's beliefs.
Aristotle believed that the heart was the main and most important organ of the body. He also came to the conclusion that the heart is a three-chambered organ.
Hippocrates estimates that the body is made up of 4 humors: blood, phlegm, black bile, and yellow bile, and an imbalance of these 4 humors causes disease.
BCE. Alcmaeon of Croton
Alcmaeon of Croton, a Greek thinker who practiced dissecting animals, examined arteries and veins and came to the conclusion that the two are similar.
Feb 21, 1200
Mid CE. Pulmonary circulation
Eminent Cairo, physician and Ibn al-Nafis, author, both discover pulmonary circulation, which is blood flow to and from the lungs.
CE. Red blood cells
A Dutch microscopist named Jan Swammerdam was supposedly the first person ever to look at and describe red blood cells.
CE. Capillary system
the carpillary system was discovered by an anatomist named Marcello Malpighi. He discovers that the carpillary system is a network of many vessels that connect the veins and the arteries together.
CE. Blood transfusion
Richard Lower performed the first ever blood transfusion, using dogs.
CE. Human transfusions
Jean-Baptiste Denis, a French physician, transfuses a boy who was suffering from a fever with lamb blood. Not long later do Doctors Richard Lower and Edmund King perform a blood transfusion to a different patient using sheep blood.
CE. Description of red blood cells
Anton van Leeuwenhoek studies red blood cells and discovers that they are about "25,000 times smaller than a fine grain of sand."
CE. Human-to-human blood transfusion
Philip Syng Physick, a Philadelphia physician, performed the very first human-to-human blood transfusion, although it was not recorded at the time.
CE. First recorded human-to-human blood transfusion
James Blundell performed the first recorded human to human blood transfusion. He injected his patient with 12 to 14 ounces of blood, and the patient died after showing the slightest bit of recovery.
CE. Bone marrow
Sir William Osler observes bone marrow and comes to the conclusion that the bone marrow makes up most of the clots found in blood vessels, and that those particular cell fragments are called platelets.
CE. Three blood groups
Karl Landsteiner discovers the three blood groups, A, B, and C (O).
CE. 4th blood group discovered
Karl Landsteiner's colleagues Alfred von Decastello and Adriano Sturli discover the fourth blood group, AB.
CE. Cross matching transfusion
Reuben Ottenberg is the first to perform a translation using cross matching, eliminating transfusion actions.
CE. Sodium citrate
Albert Hustin and Luis Agote discover that putting some sodium citrate into blood will keep it from clotting.
CE. Concentration of sodium citrate
Richard Lewisohn comes up with the correct concentration of sodium citrate to keep coagulation from happening. The amount he came up with was .2%.
CE. Citrate-glucose solution
Francis Peyton Rous and J.R. Turner create a citrate-glucose solution that makes blood able to be stored for a few weeks at a time and still be able to be used for a transfusion.
Doctor Oswald Robertson stores type O blood with citrate-glucose solution while he served in the U.S. Army. He then creates the first blood depot.
CE. Blood donor service
Percy Lane Oliver created a blood donor service right outside of his house.
CE. Cadaver blood
Doctor Serge Yudin becomes the first man to expiriment with cadaver blood in blood transfusions involving humans.
CE. "Blood bank"
The term "blood bank" was composed by Doctor Bernard Fantus, to depict the blood preservation, donation, and collection at a hospital in Chicago.
CE. Rh blood group
The Rh blood group is discovered by Karl Landsteiner and Alexander Wiener through expiriments with Rhesus monkeys and their red blood cells.
CE. Plasma shortage/ Protien seperation
During WW2 there was a plasma shortage, so a Plasma of Britian campaign is organized. Edwin Cohn discovers a way to seperate different protiens.
CE. American Red Cross
The American Red Cross decides to organize a blood donor service to give blood to the people in the war effort.Total, they collect over 13 million units of blood.
With the use of Z-rays, Max Perutz was able to figure out and identify the structure of hemoglobin.
Judith Pool uncovers that thawed frozen plasma deposits Cryoprecipitates. They help prevent hemophiliacs from needing to go to the hospital for treatment.
The first blood disease to ever be recorded is called Gay-related Immunodeficiency Disease (GRID). It later takes on the name of Acquired Immune Deficiency Syndrome (AIDS).
While looking more into the study of AIDS, researchers are able to isolate the main virus involved. They label it as lymphadenopathy-associated virus (LAV).
CE. AIDS virus
Robert Gallo identified the virus that is involved with AIDS and named it human T-cell lymphotropic virus ( HTLV III).
CE. HIV antibodies
The ELISA test was created to detect if a person had HIV or not. Blood banks and plasma centers used this test all over the world.
-2002 CE. HCV and HIV
2 more tests are created to detect blood related diseases, to detect diseases like HCV and HIV.
BCE. Ancient Egyptian doctors.
Ancient Egyptian doctors treated their patients by using bleeding.