Alcmaeon of Croton observes that arteries and veins are not similar
130 CE- 200 CE Claudius Galenus
Claudius Galenus, an important physician, proves that arteries contain blood. He believes that the system of the arteries and veins differ. Blood forms in the liver and in order to get to other parts of the body it travels through the veins
350 BCE Greek Philosopher Aristotle
Aristotle believes the heart is the central organ of the body. He begins to conduct dissections of different animals and concludes that it is a 3 chambered organ for animals and humans.
A Greek anatomist discovers that arteries are thicker than veins and that they carry blood.
Feb 18, 1200
Ibn al-Nafis discovers the pulmonary circulation. He also describes it explaining how the blood flows to and from the lungs.
William Harvey publishes his masterwork called Anatomical Treatise on the Movement of the Heart and Blood in Animals. In his work he explains how the blood is pumped by the heart in order to circulate within the body.
1658 Jan Swammerdam
Jan Swammerdam is believed to be the first person to see red blood cells and describe them.
Marcello Malpighi uses a rudimentary microscope and detects the capillary system. This system is the network of vessels that connect the arteries and the veins.
1665 Richard Lower
Richard Lower is the first person to perform a recorded blood transfusion in animals.
Anton van Leeuwenhoek
Anton Van Leeuwenhoek is able to give an idea of the size of a red blood cell. As he states, it is about "25,000 times smaller than a fine grain of sand."
William Hewson features in his book his research on blood coagulation. He includes a substance labeled "coagulable lymph" which is now known as fibrogen.
Philip Syng Physick
Philips Syng Physick performs the first human-to-human blood transfusion
Karl Landsteiner publishes a paper where he details his discovery of the 3 main blood types. These 3 main blood types are A, B, C.
Ruben Otenburg performs the first transfusion using cross matching. Cross matching is when you check the blood of donors and recipients for signs of incompatibility
Albert Hustin and Luis Agote
Albert Hustin and Luis Agote discover that adding sodium citrate to blood will prevent it from thickening.
Francis Peyton Rous and J.R. Turner
Francis Peyton Rous and J.R. Turner develop a citrate-glucose solution that allows blood to be kept for a few weeks and still be usable
Dr. Oswald Robertson collects and stores type O blood and has the first blood depot.
Dr. Serge Yudin is the first to test the ability of transfusing humans with cadaver blood.
The Soviets create a network of abilities to collect and store blood, that will be used in transfusions at hospitals.
A group of anesthesiologists are the first to store citrated blood and use it for transfusions in a hospital setting.
Federico Duran-Jorda starts the Barcelona Blood-Transfusion Service. They collect blood, test it, and store it under refrigeration
Karl Landsteiner and Alexander Wiener experiment with the red blood cells of Rhesus monkeys and discover the Rh blood group.
Dr. Isidor Ravdin treats successfully the victims of the Pearl Harbor attack with albumin to increase the blood volume.
The American Association of Blood Banks
Directors of independent, community blood banks join together to form the American Association of Blood Banks.
Carl W. Walter
Dr. Carl W. Walter creates a plastic bag for the collection of blood.
Dr. Max Perutz is able to undo the structure of hemoglobin through the use of X-ray crystallography
Kenneth M. Brinkhous and Edward Shanbrom
Kenneth M. Brinkhous and Edward Shanbrom produce a form of Factor VIII by merging large quantities of plasma. They are redissolved, treated, filtered, and centrifuged.
Dr. Judith Pool discovers that softened frozen plasmas are high in Antihemophilic Factor. Cryo has much greater clotting power than plasma.
Elliot Richardson sends the responsibility of regulating the blood banking industry from the Division of Biologics Standards to the Food and Drug Administration
The first cases of a syndrome are reported, and is later renames AIDS.
Bruce Evatt suspects that the syndrome may be blood borne. He
presents his theories at a meeting of a group of the U.S. Public Health Service.
Luc Montagnier's lab detatch the virus that causes AIDS.
Robert Gallo identified the virus that causes AIDS. He calls it HTLV III (human T-cell lymphotropic virus)
The first blood-screening test to find HIV antibodies is licensed by the US government.
Screen donated blood
More sensitive tests are developed and used to screen donated blood for infectious diseases