The transformation of surgery 1845-1918 By Annacassia Jan 1, 1846 Liston used ether as an anaesthetic Liston used ether as an anaesthetic Jan 1, 1847 Simpson used chloroform as an anaesthetic. Simpson used chloroform as an anaesthetic. Jan 1, 1848 Hannah Greener died following an overdose of chloroform Period: Jan 1, 1850 to Jan 1, 1870 Black Period of surgery continuing problems of infection and blood loss meant that the death rate remained high. Dec 26, 1853 Queen victoria used chloroform during child birth Jan 1, 1861 Pasteur published germ theory Jan 1, 1877 Lister published methods Jan 1, 1878 Koch developed steam sterliser Jan 1, 1901 Landsteiner identified blood groups Jan 1, 1905 Novocaine used as an aneasthetic Period: Jan 1, 1914 to Jan 1, 1918 World War 1 Jan 1, 1916 Rous and Turner developed a way of storing blood. Jan 2, 1916 Gilles set up plastic surgery