Medical Investigations 1 By meghenry 500 Alcmaeon of Croton distinguished veins from arteries Period: 500 to Sep 4, 2015 HIstory of Medicine Period: 500 to Dec 31, 1500 Middle Ages Sep 10, 1010 Avicenna writes The Book of Healing and The Canon of Medicine Period: Jan 1, 1300 to Dec 31, 1599 Renaissance Sep 10, 1300 Islamic hospitals offer health care for the sick Sep 10, 1490 Leonardo da Vinci dissects corpses Sep 10, 1493 Paracelsus pioneered the use of mineral and chemical remedies Sep 10, 1500 Girolamo Fracastoro named the disease syphilis Sep 10, 1590 Zacharius Jannssen invents the microscope Period: Jan 1, 1600 to Dec 31, 1899 Industrial Revolution Sep 10, 1655 Sir Christopher Wren experiments with canine blood transfusions Sep 10, 1670 Anton van Leeuwenhoek discovers blood cells Sep 10, 1680 Anton van Leeuwenhoek observes bacteria. Sep 10, 1700 Giacomo Pylarini gives the first smallpox vaccinations Sep 10, 1760 Claudius Aymand performs the first successful appendectomy Period: Jan 1, 1900 to Sep 4, 2015 Modern World Sep 10, 1900 Karl Landsteiner introduces the system to classify blood into A, B, AB, and O groups Sep 10, 1920 Edward Mellanby discovers that lack of vitamin D in the diet causes rickets Sep 10, 1922 Insulin first used to treat diabetes. Sep 10, 1925 First vaccine developed for whooping cough Sep 10, 1927 First vaccine developed for tetanus. Mar 2, 2022 Rhazes discovered difference between smallpox and measles