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Sir Humphry Davy discovers the anesthetic properties of nitrous oxide
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John Marshall is appointed Chief Justice of the Supreme Court of the United States.
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Thomas Jefferson is elected as the 3rd president of the United States in a vote of the House of Representatives after tying Aaron Burr
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The first steam-powered ferry service between New York City and Hoboken, New Jersey is started on John Steven's ship, the Juliana.
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Rene Laennec invents the stethoscope
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James Blundell performs the first successful transfusion of human blood
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Andrew Jackson, now in the Democratic party, is inaugurated as President, replacing John Quincy Adams after his sole term in office.
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Crawford W. Long uses ether as a general anesthetic
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William Morton, a dentist, is the first to publish the process of using anesthetic properties of nitrous oxide
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Ignaz Semmelweis discovers how to the prevent the transmission of puerperal fever
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Elizabeth Blackwell is the first woman to gain a medical degree from Geneva Medical College in New York
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Charles Gabriel Pravaz and Alexander Wood develop the syringe
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The Gadsden Purchase is consummated, with the United States buying a 29,640 square mile tract of land in present-day Arizona and New Mexico
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Louis Pasteur identifies germs as cause of disease
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Joseph Lister develops the use of antiseptic surgical methods and publishes Antiseptic Principle of the Practice of Surgery
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First vaccine developed for anthrax by Louis Pasteur
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First vaccine for developed for rabies by Louis Pasteur
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First successful heart surgery performed, in Germany. Surgeons repaired a stab wound in the muscle of the right ventricle.
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Felix Hoffman develops aspirin
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Karl Landsteiner introduces the system to classify blood into A, B, AB, and O groups
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First documented plastic surgery performed, on a burned English sailor.