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Jan 1, 1549
Earliest account of inoculation of smallpox in China
Pus from sores on smallpox sufferers was "inserted" into the nose. People who were inoculated caught a much less severe form of smallpox and didn't die. -
Period: Jan 1, 1549 to
History of Immunology
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Edward Jenner vaccinates against Smallpox
Jenner noticed milk maids did not catch smallpox, which killed most of its victims. He used the pus from the cowpox sores and injected a "volunteer" boy with cowpox pus. Six weeks later, he injected the boy with smallpox. The boy did not get sick. -
Louis Pasteur
Pasteur used the idea of microbes or germs causing fermentation or "spoiling" of wine milk and beer. He invented the method of heating the liquids, in order to kill any germs present. This process is known as Pasteurisation and is still used today. -
Robert Koch
Koch's Postulates show that germs cause disease, in this case anthrax. His work also set the idea of being able to work aseptically (in sterile conditions). -
Pasteur Popularises Germ Theory
Confirms the work of others in the past that microbes cause fermentation and disease. Uses this to work on the first vaccine for anthrax, cholera and rabies. -
Antibody Responses discovered
First seen by Emil Von Behring against the diseases tetanus and diptheria. He recived the first Nobel Prize for this discovery. -
Antigen-Antibody discovery
Found by Marrack that antibodies are made in response to antigens on germs. -
Anaphylaxis Discovered
The mechanism by which the Anaphylaxis allergic reaction occurs is identified.
