History of HBV By Nhd_2012 Jan 25, 1947 F. O. MacCallum differentiated HAV from HBV. Period: Jan 25, 1947 to Jan 25, 1986 Events in HBV Aug 19, 1960 Alfred Prince experimented with Aa and HBV in the blood stream. Feb 28, 1963 Blumberg and colleagues discovered Aa. Apr 9, 1967 Kazuo Okochi, Alberto Verrucci, Alfred Prince, and Blumberg linked Aa to HBV Jan 25, 1969 Blumberg andn Irving Millman's patent to create an HBV through the Fox Chase Center Sep 20, 1970 Dane Particle discovered by Dane Jan 25, 1975 Testing of the HBV vaccine begins. Mar 25, 1976 Blumberg won Nobel Prize (Medicine) for his work on HBV and Aa. Oct 17, 1981 First HBV vaccine, plasma derived. Jul 23, 1986 HBV Recombinant DNA vaccine liscenced.
