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The Renaissance begins.
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Prince Henry founded his school of navigation.
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The Ottoman Turks took over Constaninople, and the falling of the city then signified the end of the Byzantine Empire.
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Columbus sailed with his three ships to discover the New World.
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De Gama was the first to discover a water route around Africa.
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Erasmus wrote the Praise of Folly in 1509.
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Da Vinci finished the Mona Lisa in 1517.
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Martin Luther wrote/nailed on the church the 95 Theses in 1517.
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Despite the fact that he died halfway through his journey, Magellan was known to be the first man to circumnavigate the globe.
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The Aztec empire falls to Cortez in 1521.
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The Mughal Empire was founded in 1526 .
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The Spanish introduced tobacco to the Europeans.
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Pizarro conquerors the Incan Empire and takes over.
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The Anglican Church began and broke away from the Catholic Church in 1534.
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Copernicus published the Heliocentric theory.
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The Council of Trent had their first session.
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Shakespeare wrote Julius Ceasar in 1599.
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The 30 Years War began.
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He discovered the curculation of blood sometime in 1628
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Discartes published Discourse on Methon in 1637.
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The Taj Mahal was finished in 1653.
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Newton published his theory (laws of gravity).