The Olden Times By Maddy y Period: 500 to 1300 Middle Ages 659 The first use of substance for tooth fillings, which was made up of silver and tin. 754 The first pharmacy was established in Baghdad. 1200 Ibn al-Haythan came up with a new explanation for vision through his research of the optics and the anatomy of the human eye. 1231 Fredrick II promulgated a set of laws concerning medical education standards and licensure. 1289 The medical university of Montpellier was founded Period: Jan 1, 1301 to Dec 11, 1700 Renaissance Jan 1, 1348 Black Death outbreak. 1450 Started a shift in medicine towards more of a scientific approach which led to new discoveries 1500 Increased anatomical knowledge which allowed many new discoveries for human anatomy 1543 Vesalius publishes his findings on human anatomy in De Frabica Corporis Humani 1620 Peter Chamberlen invented the obstetrical forceps, used to free a baby from the whom during a difficult birth without hurting the baby or the mother. 1670 Anto van Leeuwenhoek discovers blood cells 1701 Giacomo Pylarini gives the first small pox inoculations. Period: Jan 1, 1701 to Dec 31, 1899 Industrial Revolution 1816 The first stethoscope was invented by a French physician. 1818 James Blundell performs the first successful transfusion of the human blood.. 1847 Began using chloroform for operations 1890 Rubber gloves were first used in operations. Period: Dec 1, 1900 to Dec 31, 1999 Modern World 1901 Karl Landsteiner introduces the system to classify blood into A,B,AB, and O groups. 1922 Insulin first used to treat diabetes 1960 Developed the technique of CPR. 1963 Thomas Starzl performed the first human liver transplant 1978 Doctors recorded the last fatal case of smallpox. Period: Jan 1, 2000 to Sep 5, 2019 21st Century 2001 A group of surgeons managed to implant a new generation artificial heart in a patient. 2006 Doctors began to introduce potential STEM cells and also cloned human STEM cells. 2006 First vaccine to target a cause of cancer. 2013 Development of the first advanced movement of the first prosthetic leg that communicates with the mind. 2013 Artificial Kidney and Liver grown in laboratories.