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Pope Nicholas V appointed, he begins a major program of rebuilding.
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Ottoman Turks capture Constantinople, ending the Byzantine Empire; end of the Hundred Years' War between England and France
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france vs. england war
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Leonardo moves to Florence, where Lorenzo "The Magnificent" de Medici becomes ruler
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Columbus Sails The Ocean Blue. Columbus sets out to find an alternate route to India, and instead “discovers” a “New World.”
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Syphilis starts spreading through Europe
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Europe launches African slave trade with the New World
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Martin Luther nails his theses to church door, launching the Protestant Reformation; coffee introduced in Europe
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Publication at Zurich of Coverdale's Bible, the first printed Bible in English
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John Knox, a student of Calvin, returns to Scotland and helps establish the Presbyterian Church as the official religion.
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Thirty Years' War, series of European conflicts lasting from 1618 to 1648, involving most of the countries of western Europe, and fought mainly in Germany.
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