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By 1200 Southernization went from China to the Mediterranean. Important factors of Southernization are affected by latitude. Southern parts of Asia and the Muslim Mediterranean got to grow and produce cotton, sugar, cinnamon, pepper, and fine spices. After 1200 Southernization reached its max. This took place because the hemispheres had major changes. The hemispheres changed in wealth, prestige, and distribution of power. In the Western Hemisphere the great powers fell from their rank.
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The grandest conquers in the thirteenth century were the Turkish invaders and the Mongol cavalries. In the twelfth or thirteenth century the Arabs were the first to use a compass on Mediterranean waters.
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In 1204 Venetians took over Byzantine empire's capital.
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The years 1212 to 1270 christians took over Southern Spain, excluding Gana.
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Mali created a large empire wanting to seek revenge on the Ghana's smaller empire.
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In 1261 Genoese teamed up with Byzantines to take control over Constantinople from the Venetians. After this the Genoese were granted privileges for trade in the black Sea. Italy was eventually connected to Mongolian trade routes.
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In the fourteenth century block printing, gunpowder, and cannon first appeared in Italy.
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In these trade route the bubonic plague was passed around. It first started out in China and started to spread everywhere.
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Rats and lice containing the plague traveled westward in saddlebags with the Mongolian messengers. By 1246 the plague had arrived at the Black Sea port and from there it went to the Middle East and Europe.
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In 1450 in every major Italian city there were thousands of Asian slaves.