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Alexander III (Alexander the Great) takes power when his father is assassinated by a servant during an invasion
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Relations with the Athenians turn sour when a naval ship checkpoint is set up at the Athenian colony Amphipolis; A new Thraceian kingdom under Sictalces began to threaten Macedonian territory.
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Archelaus is assassinated by victims of his lust
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After a long period of conquering and other successes, the invasion of the Persian Xerxes brought expansion to a halt
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Philip, the ruler after Archelaus is murdered, is taken as a Thracian hostage at the age of fifteen for three years
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During the 'Social War' of Athens, Philip laid siege to the colony Amphipolis