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India starts to produce and trade cotton textiles to replace the wool clothing worn in most countries up to that point.
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Sugarcane becomes a trade staple for India and Persia.
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Bananas enter the trade route.
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Ivory is traded between Africa and India, Southeast Asia, and China.
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Indigo plant is traded and used to dye Chinese silks.
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Dhows is used to transport merchandise.
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Scylax makes voyage into the Indian Ocean and introduced the trade regions to Persia and encouraged more trade expeditions Persia.
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Cinnamon and Cassia enter the Indian-Ocean trade route.
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Alexander the Great conquers Western Asia and begins Hellenistic Period.
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A fleet from Indus River to Persian Gulf travels on behalf of Alexander the Great.
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African and Mediterranean networks join into one with the Mediterranean trading wine and oil, India trading spices and pepper, and Persia and Egypt trading grain.
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Ptolemies learns about the monsoon system in the Indian Ocean.
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The Isthmus of Kra, a thin piece of land that separates Indian Ocean and China Sea is crossed and allows travelers to trade more goods.
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The cities of Funan transfer trade goods from Indian Ocean and South China Sea into inland trade routes.
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Zhang Qian brings Chinese trade from Silk Road trade routes.
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Cyzicus disappeared on the return voyage from the monsoon wind system.
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A period of peace begins in Rome under Augustus Caesar that allows trade to flourish.
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Birth of Jesus in Nazareth who begins Christianity after crucifixion around 30 CE.
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Apostle Paul travels and spreads Christianity around Mediterranean.
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Due to contact with merchants, the Han and Roman empires suffer large-scale outbreaks of disease.