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This is the general rough period of the Renaissance in Europe, as it slowly transitioned into something else,
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Prince Henry opens his school of navigation
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Constantinople was seized by the Ottoman Turks from the Byzantine Empire
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Christopher Columbus lands in the Bahamas
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The Treaty of Tordasillas was signed, which split land in the New World between Spain and Portugal
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The mana Lisa was painted. However, it is thought that it might have been continued to be worked on all the way to 1517.
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Erasmus wrote Praise of Folly
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Martin Luther posted the 95 Theses on a church door.
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The Spanish introduced tobacco to Europe
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Hernán Cortés of Spain captured the Aztec capital Tenochtitlan
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Ferdinand Magellan set sail from Spain to try to circumnagivate the world
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The Mughal Empire was founded by Babur
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Francisco Pizarro of Spain conquered the Inca Empire in 1532 in the Battle of Cajamarca
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King Henry VIII separated from the Catholic Church with his new denomination
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Copernicus's Helicentric theory was published, which angered many people
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This concil defined and reinforced official Catholic beliefs
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England defeated the "Invincible" Spanish Armada. Jul 29, 1588
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The Shakespeare play Julius Caesar is believed to be written this year
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Galileo made his own telescope, where his was able to find out lots of new things about the universe and back up Copernicus's theory
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A long war started as a fight between the Protestants and Catholics, but slowly turned into a political war1618–1648
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William Harvey published De Motu Cordis, which contained his discoveries of circulation of blood
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Discartes wrote the book Discourse on Method, where he designed a way of questioning and reasoning
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Taj Mahal's main mausoleum was finished this year.
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Sir Isaac Newton published Philosophiæ Naturalis Principia Mathematica, which contained his laws of gravity