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In 1545 an outbreak of smallpox killed 8,000 childen in India.
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Persian physician Rhazes is the first to identify smallpox,from measles,and to suggest blood as the cause of infectious disease.
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Edward jenner makes a vaccine against smallpox. He rubs cowpox pus on an 8 yr old and 6 weeks later he exposes him to smallpox that he didn't get.
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John snow discovered that cholera was spread by water and he drew a map of where all the water pumps in the area were and identified that one area was mosty infected because they all drank the same water from the same pump.
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Louis Pasteur establish the germ theory of disease. According to germ theory, a specific disease is caused by a specific organism. Before this discovery, most doctors believe diseases are caused by spontaneous generation