Biotechnology Time Line By kr3433 100,000 BCE Wasterwater Treatment 100,000 BCE in vitro culture 5000 BCE Discovery of Vinegar 3400 BCE Archaeologists Have Unearthed Ceramic Vessels of Beer 2000 BCE Biotechnology Used to Leaven Bread 2000 BCE Production of Cheese Begins 2000 BCE Fermentation of Wine Begins 1700 Yogurt was Brought to North America 1784 First Artificial Insemination Was Reported In a Dog by the Scientist Lazzaro Spallanzani 1796 Smallpox Vaccine, the First Successful Vaccine, Was Developed by Edward Jenner 1833 Enzymes Discovered 1833 William Beal is Born 1857 Discovery of Fermentation 1857 Louis Pasteur Discovered the Fermentation Process of Yeast 1857 Louis Pasteur Proposes that Microbes Cause Fermentation 1865 Gregor Mendel Discovers the Laws of Inheritance 1865 Mendel Published his Discovery on Genes 1866 Gregor Mendel Discovers the Basic Principles of Genetics 1890 People Started Breeding Plants 1920 Farmers Started to Use Bt as a Pesticide 1921 Discovery of Insulin 1928 The First Antibiotic, Penicillin, Was Discovered by Alexander Fleming 1953 James Watson and Francis Crick Discover the Double Helical Structure of DNA Feb 28, 1953 Francis Crick and James Watson Discover DNA 1960 The Green Revolution Started 1970 Round Up Ready is First Patented 1972 Genetic Engineering Was First Accomplished 1980 Flavr-Savr Tomato is Genetically Engineered 1987 Transgenic Plants Were Genetically Engineered 1989 Bioremeditation Begins 1995 The First Animal was Cloned 1999 Golden Rice Generation Begins