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From 303 to 311, the Roman persecution of Christians formally ended.
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Julian the Apostate rises to be Roman Emperor and attempts to revive paganism in empire, but his efforts are futile.
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Constantine the Great formally establishes Roman toleration of Christian religion.
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Council called by Constantine to formalize Christian scripture as Roman Catholic doctrine and finalize the nature of Jesus Christ
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The first Basilica of St. Peter built in Rome. Also, Constantine establishes Constantinople as a capital of Rome on the former Greek colony of Byzantanium. This will create division of Roman Catholic Religion in years to come.
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In scholarship, knowledge moves from recording on scrolls to the formalization of storing knowledge in written books.
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In only eight days, Ambrose goes from a candidate for leadership to a full bishop due to popular social demand.
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Alaric, the king of the Visgoths, captures and sacks Rome.
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The Philosophy of alchemy formally develops in such concepts as ''the philosopher's stone' and 'the elixir of life.'
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Due to Theodosius' actions forty years prior, barbarians begin to settle into Roman provinces and influence the population.
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Ambrose was born in what is now Tier, Germany. His widowed mother was helped by her nun sister to raise the child.
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Ambrose develops the use of hymn singing in church worship and even composes some hymns himself.
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Emperor Theodosius rises as Roman ruler. By the year 395, he will be the last ruler of a totally united Roman Empire. The Empire splits and never again unites under one political ruler. Church rule is established as power over the political when Ambrose excommunicates Theodosius over a massacres ordered by the Emperor.