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President Thomas Jefferson brought the Louisiana Territory from France for $15 million which doubled the size of the United States and provides a large area to the west of the country for expansion.
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The construction of the Cumberland Road began in Maryland and stretched 600 miles into the Northwest Territory.
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Construction of the Erie Canal begins that stretched for 363 miles allowing the passage of boats inland carrying produce and passengers from the Atlantic Ocean to Lake Erie.
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The 'Stourbridge Lion' was the first operational locomotive on an American railroad.
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Mexican troops attacked the Alamo Mission killing all but two Texans.
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People begin to travel west in wagon trains on the Oregon Trail. Around 300,000 people would take the trail over the next 20 years.
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The first telegraph line is established. Morse code is sent by Samuel Morse from Washington to Baltimore.
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A journalist, John O'Sullivan, first uses the term "Manifest Destiny" to describe the westward expansion of the United States.
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The United States officially claims Texas as a state, eventually leading to the Mexican-American War.
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A war fought over the rights to Texas. After the war, the United States paid Mexico $15 million for land that would later become California, Texas, Arizona, Nevada, Utah, and parts of several other states.