- 
  
  Blaise Pascal in vented the first syringe that used what is now called the Pascal's law.
 - 
  
  Lady Mary Mortly Montague introduced variolation in England
 - 
  
  Edward Jenner preformed the first vaccine by infecting his eight year old son with the cowpox virus to prevent him from getting the much more deadly small pox
 - 
  
  Charles Gabriel Pravaz and Alexander Wood developed a needle fine enough to pierce the skin.
 - 
  
  Louis pasture created the first attenuated bacterial vaccine
 - 
  
  Louis Pasture uses the first rabies vaccine in humans
 - 
  
  The biological control act was formed in response to tainted vaccinations. It required both liscensing and inspection of manufactures.
 - 
  
  ,A live virus is misted into nose instead of shots leading to a much quiter vaccination process.
 - 
  
  Influenza vaccination is recommended for those 6 months and older.