Malaria throughout History

By Safet Husic

  • Discovery of the Plasmodium parasite

    Charles Loius Alphonse Laveran discovers the malaria parasite in the blood of a patient during his time as a French army surgeon in Algeria

  • Discovery of separate malaria species

    Camilo Golgi contributes to the study of malaria by identifying that there was more than one form of the disease. One had a tertian periodocity and one had a quartan periodocity.

  • Discovery of the transmitter of malaria

    Ronald Ross determined that malaria parasites were transmitted to humans through infected mosquitos

  • United States Public Health Service malaria control

    Malaria control activities (vector controls) are set up in affected regions of the United States

  • Discovery of the insecticidal properties of Dichloro-diphenyl-trichloroethane

    DDT used at the end of World War II for malaria control, demonstrated to be effective as it killed of malaria infected mosquitos.

  • Discovery of antimalarial properties of Chloroquine.

    Allied Scientists confirm that Chloroquine is an effective antimalarial drug

  • US cleared of Malaria as a significant health problem

    The United States are cleared of Malaria as a significant health problem

  • Malaria eradicated from the US

    Malaria is eradicated in the US

  • Discovery of Chloroquine resistance

    Some malaria parasites discovered to have developed a resistance to Chloroquine

  • Increase in malaria on a global level

    Financial constraints and reduced control measure see an increase of malaria 3-fold

  • DDT is banned

    DDTs harmful nature is recognised, resulting in its ban

  • Eradication of Malaria in Europe

    Europe rids itself of the malaria disease

  • Antigen diagnostic tests

    Antigen based diagnostic tests for malaria are developed

  • Discovery of the antimalarial Mosquirix

    Mosquirix antimalarial vaccine is developed

  • Mefloquine antimalarial

    The mefloquine antimalarial is approved for use.

  • Childhood malaria mortality reduced in Africa

    Childhood mortality to malaria reduced by roughly 20-30% due to the use of antimalarial coated bednets

  • WHO provide antimalarials to African communities

    The World Health Organisation train volunteers to travel to Africa and administer antimalarials to various communities

  • Malaria death toll

    985,000 malaria deaths worldwide

  • Sequencing of genomes

    The Plasmodium falciparum parasite genome is sequenced

  • Funding

    Increasing in global funding to fight malaria, AIDS and other diseases

  • Phase II trials of Mosquirix

    Phase II trials determined to provide partial protection in some African nations.

  • Artesunate development

    Severe cases of malaria are combated through the antimalarial Artesunate

  • Malaria Day

    UN develop the worlds first Malaria Day in an attempt to close the gaps in coverage for malaria prevention.

  • Phase III Mosquirix Vaccine

    Trials for the Phase III vaccine begin in Africa

  • Reduced death toll worldwide

    781,000 malaria deaths worldwide

  • Further decrease in mortality

    655,000 deaths worldwide

  • World's first licensed antimalarial

    Mosquirix is licensed for use worldwide by the European Union

  • Mosquirix vaccine test

    African nations are invited to test run the Mosquirix vaccine for children from the ages of 5-9 months