Aztecs By blaker65 Feb 17, 1519 Cortes sets out to Cuba Jul 3, 1519 Moctezuma and Cortes meet Aug 6, 1519 Cortes takes Moctezuma hostage Oct 23, 1519 The Spanish massacre thousands of Aztecs while preparing for their religious festival Mar 16, 1520 Moctezuma dies May 2, 1520 The Aztecs begin to die from smallpox Jun 25, 1520 The Spanish form a second attack on the now weakened Aztecs Aug 28, 1520 The last group of Aztecs surrender Sep 11, 1520 spanish destroy aztec religion symbols Apr 4, 1521 Cortes becomes governor and captain-general of New Spain