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Variolation was used a a major way to prevent disease before vaccination, either through the grafting of smallpox scaps onto the skin of an uninfected person or coming into contact with an infected person or infected matter in a controlled setting.
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Edward Jenner inoculated an 8-year-old boy, James Phipps, with matter from cowpox lesions in hopes of making him immune to smallpox. -
Edward Jenner inoculated the boy again in July. This time, though, he used matter from a smallpox lesion. When the boy developed no symptoms, Jenner assumed that the protection was complete.
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Edward Jenner was found dying in his study after having a massive stroke. -
Louis Pasteur and his colleagues injected the first of 14 daily doses of rabies vaccine into a 9-year-old boy, Joseph Meister, after he was severely bitten by a rabid dog. -
Edmond Nocard demonstrated the protection and immunization of tetanus by using passively transferred antitoxin as well as deactivating the bacteria and spores. -
The FDA was founded in order to regulate the food and drug commerce. They also set into play regulations for vaccine development and whether they can or cannot be used on the human population depending on studies done on the medicine. -
The first inactivated polio vaccine was created by Jonas Salk, and was licensed on the same day that the results of it's testing were released. Salk originally tested the vaccine on him and his family. -
Vaccines are developed for all 3 strains of polio, and saw widespread use across the world in an attempt to eradicate poliovirus.
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The World Health Assembly announces that the world is free from smallpox and reccomended a cease of vaccination. -
The measles, mumps, rubella, and varcella vaccine was licensed and became one of the recommended vaccinations for children. -
Pfizer's Covid-19 vaccine was given emergency use authorization by the FDA and was distributed around the world.