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The Europeans brought an epidemic of smallpox, which kills many Natives on the New England Coast. -
Verrazzano was sailing for France, but he soon became the first to explore the East coast of the now United States of America. -
A Frenchman, Jacques Cartier, navigates the St Lawrence River and names an island along the River Montreal. -
Over 100 English settlers find Jamestown on the coast of Virginia. -
A French explorer, Samuel de Champlain founded the colony of Quebec. -
While exploring for the Netherlands, Henry Hudson claims land that will become New Netherland. -
The Duke of York drives out the Dutch in New Netherland. He claims the colony for England and renames it New York. -
King Philip's war begins in Massachusetts between colonists and Natives. -
Sieur de la Salle claims the lower Mississippi Valley for France and names it Louisiana. -
A war between the British and the French began over disputed land claims in the Ohio River Valley. -
Pilgrims from England found an English colony in Plymouth, Massachusetts.