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Although against Valasquez's orders, Cortes sails from Cuba to Mexico. Land that has yet to be explored and/or documented.
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Tlaxcalans attack the Spanish. The Tlaxcalans were a group of indingenous people located East of Mexico.
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The Tlaxalans form an alliance with the Spanish, to defeat the Aztecs.This lead the Spanish to compromise a situation that allowed the territoy to remain mostly in tact through the years of colonial period.
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After countless times of refusing to meet Cortes, Moctezuma peacefully received Cortes. He deliberately welcomed Cortes and his men, in hopes of finding their weakness for future references. That later changed and ideas such as Cortes and his men being forms of the serpent god came to show in Cortes' letters
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The Spanish massacre thousands of Aztecs while preparing for their religious festival
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The Aztec begin to die from smallpox. As said before, Cortes had ignored the order of the Cuban governor. The governor sent out Pánfilo de Narváez to chase after Cortes, however one of Narvaez's forces contained an active case of small pox, which spread like wildfire among the Aztecs
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The Spanish retreat after the Aztecs gather arms. Managing a narrow escape with their rearguards massacred, the Spaniards are able to leave with some treasure.
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Moctezuma dies. Either by the hands of the Spanish or showers of rocks by his own people.
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The Spanish form a second attack on the now weak Aztec. The Aztec fall in numbers due to the epidemic
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After the down fall of the Aztec Empire, Cortes becomes the governor and captain general of New Spain
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The last surviving group of Aztecs surrender to Cortes. Thus the Aztec Empire ceasing to exist
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