Aztec Civilization By Corvus 600 First Nahuatl speaking humans begin to settle in Mexico. Period: 600 to 1325 Foundation of a new empire. 1100 Mexica travel south from their northern homeland to find a new place to settle. 1300 The Mexica settle in Tizapan 1325 Tenochtitlán is settled. Period: 1350 to 1454 Expanding the empire. 1376 First Huey Tlatcani, Acamapichitli, rules. 1390 Construction of Templo Mayor begins in Tenochtitlán. 1395 The second Huey Tlatcani, Huitzilihuitzli, rules. 1417 The third Huey Tlatcani, Chimalpopoca, rules. 1427 War against the Tepeneca, who have dominated central Mexico, begins. 1427 The fourth Huey Tlatcani, Itzcoatl, rules. 1430 The Tepeneca are conquered. 1431 The Triple Alliance is established. 1440 The fifth Huey Tlatcani, Montezuma I, rules. 1452 Tenochtitlán is severely damaged in a flood. 1469 The sixth Huey Tlatcani, Azayactl, rules. Period: 1469 to 1510 Height of the empire. 1481 The seventh Huey Tlatcani, Tizoc, rules. 1486 The eighth Huey Tlatcani, Ahuitzotl, reigns. 1487 Dedication of the Templo Mayor in Tenochtitlán. 1492 Christopher Columbus lands in Santa Domingo 1502 Reign of famous Huey Tlatcani, Moctezuma II, the ninth of the Aztec kings. Period: 1517 to 1525 Collapse of the empire. Mar 4, 1519 Hernan Cortez lands on the peninsula of Yucatan. Nov 8, 1519 Hernan Cortez arrives in Tenochtitlán. 1520 The tenth Huey Tlatcani, Cuitahauc, rules but dies of smallpox within the same year. 1520 Hernan Cortez sides with the Tlaxcala, enemies of the Aztecs, and begins assault on the Aztec empire. 1520 Cuauhetemoc, the eleventh and last Huey Tlatcani, rules. 1521 Fall of Tenochtitlán. Cuauhetemoc surrenders to Hernan Cortez. 1522 Tenochtitlán begins reconstruction as Mexico City, the capital of New Spain. 1525 Cuauhetemoc is hung by the Spanish.