Aztec an Spain By KIller12345678910 Feb 17, 1519 Cortes sails for Mexico from Cuba Mar 20, 1519 Tlaxcalans form alliance with the Spanish May 11, 1519 Tlaxcalans attack the Spanish Jul 3, 1519 Moctezuma and Cortes meet Aug 9, 1519 Cortes takes Moctezuma hostage Oct 23, 1519 The Spanish massacre thousands of Aztecs while preparing for their religious festival Feb 9, 1520 The Spanish retreat after the Aztecs gather arms Mar 16, 1520 Moctezuma dies Apr 24, 1520 The Spanish attempt to escape from Tenochtitlan but are stopped by the Aztecs - later referred to as the Noche Triste May 2, 1520 The Aztecs begin to die from smallpox Jun 25, 1520 The Spanish form a second attack on the now weakened Aztecs Aug 28, 1520 The last group of Aztecs surrender Apr 4, 1521 Cortes governor and captain-general of New Spain