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Spainish needed someone to explore the West Indies, so they hired the Italian Columbus to do so. He thought he had found the West Indies, when he really just found America.
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Africans were put to work on plantations, and they were first brought in by the Spainish.
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Cortes conquers the giant Aztec empire. It was his 200 soldiers against about 20,000 Aztecs. Cortes defeated them with guns, germs, and steel.
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Pizarro conquers the Incan Empire with guns, germs, and steel.
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Jamestown, a small port colony, second colony in America; survived very long.
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Plymouth was found by the English Puritans looking to practice their Christianity somewhere else.
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British fought the French over land East of the Mississippi and part of Canada.