American History By summerpowers2002 1492 Columbus "discovers" America Thought he was in India but was in America instead. 1519 Hernando Cortez and the Conquistadors Conquered the Aztec empire. 1532 Francisco Pizarro claimed new colonies Conquered the Inca empire. 1539 Hernando De Soto assisted Pizzaro First to discover and cross the Mississippi river. Period: 1565 to 1608 Spanish settlement in the Americas Conquered Native Americas and established New Spain.
