Main events in the context of Tylenol case (1984)

Timeline created by rosalbavega
  • Food and Drug Act Requires that drugs be shown to be safe before marketing. This leads to the need for human trials.

  • Bristol Myers incorporates new packaging regulations for pills

  • U.S. President meets Robert Goodman and the Reverend Jesse Jackson

    U.S. President Ronald Reagan meets with Navy Lieutenant Robert Goodman and the Reverend Jesse Jackson at the White House, following Lieutenant Goodman's release from Syrian captivity.
  • The United States and the Vatican establish full diplomatic relations

  • The Apple Macintosh is introduced

  • STS-41-B: Space Shuttle Challenger is launched on the 10th space shuttle mission.

  • STS-41-B: Space Shuttle Challenger makes the first shuttle landing at the Kennedy Space Center.

  • Iran accuses Iraq of using chemical weapons

  • A year-long strike action begins in the British coal industry

  • Indian Squadron Leader Rakesh Sharma is launched into space, aboard the Soyuz T-11

  • U.S. President Ronald Reagan calls for an international ban on chemical weapons.

  • The Soviet Union announces that it will boycott the 1984 Summer Olympics in Los Angeles, California.

  • Bristol Myers launch drugs for depresion and anxiety

  • Glucotrol® (glipizide), for diabetes, is launched.

  • Salyut 7: Cosmonaut Svetlana Savitskaya becomes the first woman to perform a space walk.

  • Bristol Myers delivered 43 millions of coupons of $1.50 equivalent of 24 or 30 tablets of Datril

  • Half a million people in Manila demonstrate against the regime of Ferdinand Marcos.

  • Extra Strength TYLENOL Caplets launch

    • Advil was introduced in the United States in 1984 under the brand name "Advil". Anyone could buy it without a prescription for the treatment of headaches, dental pain, migraine and menstrual pain. It is estimated that by 1985, over 100 million people had been treated with ibuprofen in more than 120 countries.
  • EXCEDRIN

    In 1984, Bristol-Myers signed an agreement with Upjohn, which enabled it to introduce Nuprin, a new nonprescription form of ibuprofen pain reliever. With the agreement, Bristol-Myers again gained the means to take on Tylenol once again. It also pitted the firm against American Home Products, which already sold a pain reliever under the Anacin brand, and was planning to launch a new ibuprofen-based product called Advil.
    At this time, Bristol-Myers entered the market for drugs used to treat anxiet
  • The Sandinista Front wins the Nicaraguan general elections.

  • Indian Prime Minister Indira Gandhi is assassinated by her 2 Sikh security guards . Riots soon break out in New Delhi, and some 2,700 Sikhs are killed

  • United States presidential election, 1984: Ronald Reagan defeats Walter F. Mondale with 59% of the popular vote

  • A series of explosions at the PEMEX Storage Facility at San Juan Ixhuatepec, in Mexico City, ignites a major fire and kills about 500 people.

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    The 1984 Summer Olympics are held in Los Angeles, California.

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    ADVIL Need for Mass Production

    As sales increased, Whitehall Labs, the US distributor of Advil, quickly realized that Boots (the original manufacturer) could not keep up with demand. Boots was essentially making the product manually. Michael Dryden of the Whitehall R&D staff was assigned to form a team and create an automated manufacturing process as soon as possible. Dryden hired Guido Melenger, the head of a small pharma scale-up firm, to come up with an automated process.