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Agricultural Revolution begins in Mexico.
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The city of Cahokia flourishes in North America
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Aztec empire founded in Central Mexico
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Christopher Columbus makes his first voyage across the Atlantic to the Americas
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Spaniards bring first enslaved Africans to the Americas
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Ponce de Leon lands in Florida
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Martin Luther launches Protestant Reformation
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Cortez begins the Spanish conquest to Mexico
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Pizzaro subdues the Quechua Empire in south America for Spain
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Spanish Fort at St. Augustine (first permanent settlement in present day US)
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Raleigh's Roanoke Island venture
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English Navy defeats the Spanish armada
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Iroquois Confederation is founded
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The London Company sponsors a colonizing expedition to Virginia
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Tobacco becomes an export staple for Virginia.
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Dutch bring a ship of 20 African slaves to Virginia, marking the beginning of slavery.
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Mayflower lands in Cape Cod with 101 colonists
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First town government established in Dorchester, Massachuestets
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Anne Hutchinson is banished from Massachusetts for committing acts against the Puritan beliefs
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Rhode Island enacts the first law making slavery illegal
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Pueblo Revolt- Rising of Indigenous peoples against the Spanish coloniosts
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Quakers in Pennsylvania make a formal protest against slavery.
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Currency Act banning paper money in Americas