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Columbus set foot on what is now North America, thinking it was India. He discovered and traded with Natives and took many resources.
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Jacques Cartier left France to find wealth using a water path from France to Asia. Along this path he discovered what is now Canada.
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Hernando De Soto reached Ischi and explored the lands.
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Coronado couldn't find wealth where he was so he moved his army east to the pueblos around Albuquerque.
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Pedro Menéndez de Avilés landed on a shore which is currently known as Florida.
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Oñate went off to settle New Mexico by King Philip II of Spain.
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Champlain set off on another expedition up the St. Lawrence. They constructed a fort in what is now Quebec City.
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Marquette and Joliet left and headed their canoes south along Michigan to present-day Green Bay, Wisconsin.
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The Pueblo people uprised against Spanish colonizers.