In May 1796, Edward Jenner found a young dairymaid, Sarah Nelms, who had fresh cowpox lesions on her hands and arms . On May 14, 1796, using matter from Nelms' lesions, he inoculated an 8-year-old boy, James Phipps. The boy developed mild fever and discomfort in the axillae. Nine days after the procedure he felt cold and had lost his appetite, but on the next day he was much better. In July 1796, Jenner inoculated the boy again and Jenner concluded that protection was complete.