- 
  
  Verrazzano, sailing for France discovers New York Harbor.
- 
  
  Frenchman Jacques Cartier navigate the St. Lawerence River names an island along the River Montreal.
- 
  
  Jamestown is founded on the coast of Virginia by 100 English settlers.
- 
  
  French explorer, Samuel de Champlain, founds the colony of Quebec.
- 
  
  Henry Hudson, exploring for the Netherlands, cliams land that will become New Netherland.
- 
  
  An epidemic of smallpox, brought by Europeans, kills many native Americas on the New England coast.
- 
  
  Pilgrims from England found an English Colony in Plymouth, Massachusetts.
- 
  
  The Duke of York drives out the Dutch in New Netherland. The Duke of York claims the colony for England and renames it New York.
- 
  
  King Phillip's War begins in Colonial villages of Massachusetts, between colonist and Native Americans.
- 
  
  Sieur de la Salle explores the lower Mississippi Valley river and claims the valley for France and names it Lousisna in Honor of the French King Louis XIV.
- 
  
  War between the British and French & Indian War. The war is fought over disputed land clains in the Ohio Valley.