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The U.S. Capital is moved from Philadelphia to Washington DC.
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The U.S. Congress meets in Washington DC. for the first time.
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Thomas Jefferson is inaugurated as the third president in Washington DC.
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The U.S. agrees to buy the Louisiana Territory from France for $15 million.
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Louis and Clark embark to find a route to the Pacific Ocean.
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James Madison is inaugurated as the fourth president,
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U.S. declares war on Britain over British interference with American maritime shipping and westward expansion.
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British capture Washington, DC, and set fire to the White House and Capitol.
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Francis Scott Key writes the Start Spangled Banner as he watches the attack on Fort McHenry at Baltimore.
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The Treaty of Ghent is signed and marks the end of the war.
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James Monroe is inaugurated as the fifth president.
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Spain agrees to cede Florida to the U.S.
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In an effort to maintain the balance between free and slave states, Maine (formerly part of Massachusetts) is admitted as a free state so that Missouri can be admitted as a slave state; except for Missouri, slavery is prohibited in the Louisiana Purchase lands north of latitude 36°30'.
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John Quincy Adams is inaugurated as the sixth president of the U.S.
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Construction is begun on the Baltimore and Ohio Railroad, the first public railroad in the U.S.
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Andrew Jackson is inaugurated as the seventh president.
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Nat Turner, an enslaved African American preacher, leads the most significant slave uprising in American history.
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Harriet Tubman escapes from slavery and becomes one of the most effective and celebrated members of the Underground Railroad.
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Alexander Graham Bell made the first successful telephone call, saying, "Watson, come here, I need you."