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Ukraine declares independence: Ukrainian People's Republic set up. Numerous rival governments vie for control for some or all of Ukraine during ensuing civil war.
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Approximately 7 million peasants perish in man-made famine during Stalin's collectivisation campaign.
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Ukraine suffers terrible wartime devastation as Nazis occupy the country until 1944. More than 5 million Ukrainians die fighting Nazi Germany. Most of Ukraine's 1.5 million Jews wiped out by the Nazis.
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Stalin deports 200,000 Crimean Tatars to Siberia and Central Asia following accusations of collaboration with Nazi Germany.
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A reactor at the Chernobyl nuclear power station explodes, sending a radioactive plume across Europe. Desperate efforts are made to contain the damaged reactor within a huge concrete cover. Many armed forces personnel die of radiation sickness.
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Ukraine declares independence following attempted coup in Moscow: 90% vote for independence in nationwide referendum in December.
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Ukrainian military accidentally shoot down Russian air liner over the Black Sea, killing all 78 on board. Defence Minister Olexander Kuzmuk resigns.
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Russia stops all gas supplies to Ukraine after collapse of talks to end row over unpaid bills and prices, leading to shortages in southeast Europe. Supplies are restored a week later when Ukraine and Russia sign a 10-year deal on gas transit.
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Ex-President Leonid Kuchma is charged over the 2000 murder of journalist Georgiy Gongadze. He denies any part in the killing.
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Government resigns to allow a number of ministers, including Prime Minister Mykola Azarov, to take up seats in parliament. Government remains in office on an acting basis.
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After months of failed efforts at compromise, the Kiev protests see their deadliest week. At least 77 people die and police are accused of using live ammunition. The EU imposes targeted sanctions, protesters storm government offices in the east, officials begin deserting the ruling party.