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Smallpox originated in the first agricultural civilizations in Africa in roughly 10,000 BCE.
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began roughly 10,000 BCE but no one is sure when exactly.
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Hittitie armies were infected by prisoners of war from Egypt, further spreading the disease.
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Doctors and others did not think of smallpox as a big deal until after the bubonic plague ended, because that is when smallpox became more deadly. It is unknown the exact time smallpox infected Europe.
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Around 250 BCE is when small pox infected China
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As people started sailing across the Atlantic in search of new land, adventure, and many other things, they also brought with them and picked up the smallpox disease.
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Spanish explorers traveled to Puerto Rico and brought with them the smallpox disease causing yet another outbreak but this time in Puerto Rico. 30,000,000 casualties.
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when a chinese emperor died, his son supported inoculation with a letter
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Thomas Sydenham came up with the idea that treatment of mild cases of smallpox did more harm than good
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Queen Mary II died of a form of smallpox
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Small pox brought mass terror and deaths to tribes along the Great Lakes.
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Lady Mary Montagu brought the practice of variolation to England
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Catherine the Great of Russia had a secret inoculation surgery in which was successful, causing others to follow behind
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Edward Jenner found the vaccination for smallpox when he noticed that those who had cowpox were immune to smallpox.
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Boston was hit with the disease where more than half the popultion was infected. This affected the Revolutionary War because the soldiers- both american and brittish- were affected.
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Dr. Jean de Carro suggested that inoculation should be eliminated, saying, “It is inconsistent for a government to encourage vaccination and not forbid inoculation.”
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The New York Board of Health established a vaccine farm in Lakeview, New Jersey.
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although a vaccination was invented and used, there was still some communites that had strong suspicion
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Vaccinations were limited at this point in history; therefore epidemics were occuring
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When European explorers traveled to North America they gave the smallpox disease to the natives.
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The U.S. Congress passed "An act to regulate the sale of viruses, serums, toxins, and analogous products," later referred to as the Biologics Control Act
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The U.S. Supreme Court in the case of Jacobson v. Massachusetts upheld the constitutionality of mandatory smallpox vaccination programs to preserve the public health.
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many U.S. schools did not allow children to attend school before they had been vaccinated.
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although vaccinations proved safe and effective, there were still those that opposed it.
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The Brittish Medical Journal published an article showing the fatality rate in England and Wales
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Dr. Benjamin Rubin of Wyeth Laboratories patented the bifurcated needle for delivery of smallpox vaccine. Using bifurcated needles for vaccination required less vaccine material for each dose, and was easier than previous methods.
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The World Health Organization initiated a world wide eradication campaign against small pox
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a farmer, Benjamin Jesty, infected his family with cowpox to prevent them from getting smallpox-- which was successful
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English physician S. Monkton Copeman showed that adding glycerin to lymph acts as a germicide
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Although smallpox is not eradicated, it is no longer the problem it was many years ago. We now have vaccinations and cures and if someone does become infected with the diesease, we have answers.
