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Actually in 53 B.C.The parthians realized that money was to be made in the east and sent trade expeditions to the east.
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This city was the most well populated starting point of the silk road at over 2 million people. This city was a major way point for the road.
742 A.D. -
In his book Marco Polo wrote about a thousand carts of silk being imported to the capital a day.
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Started in 138B.C.
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Minor splits were formed between the Khans of the mongol empire. A resurgence of chinese nationalism and local rebellions the Yuan dynastery was replaced by the Ming dynasty. The Ming dynasty held isolationism as a value and the barriers in the east and west went up.
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138B.C. Emporer Wu Ti sends an emissary to forge an alliance. The emissary finds Chinese goods across the mountains and gets the idea for the silk road.