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He is the son of Vasili III, who ascended the throne after his father passed away
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When his father died he was only 3 but left him with a stable and expanded grand duchy as well as fear of assassination, and being constantly ignored.
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She died suddenly, most likely from poison
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Ivan IV gets married to his wife. The start of something disastrous
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After recovering from a high fever, he left the grace period of his ruling and entered the "dark period". A period where he caused Russia damage
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Tsarevich Ivan Ivanovich of Russia
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Feodor I of Russia was Ivan's second born child.
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Ivans wife, Anastasia Romanovna died from an illness. This left Ivan with emotional and physical torture/pain.
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Ivan IV abandoned the capital out of paranoia with some of his court
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He raised a bodyguard of 1,000–6,000 men which helped him in his ruling
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After his daughter and law, Elena was dressed inappropriately according to Ivan, he attacked her causing a miscarriage. This then lead to Ivan Ivanovich (Ivan the terrible's oldest son) to defend his wife and get killed. His emotional distress most likely lead to murdering his son.
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Supposedly, he died after being treated for a disease known as syphilis by mercury poisoning. He was getting ready to play a game of chess when he had a stroke