blood timeline

  • 2500 BCE

    Egyptians used bleeding to treat patients, heiroglyphics sows patients being bled from the neck and feet.
  • 350 BCE

    Aristotle "discovers" that the heart is the central organ of the body.
  • 450-400 bce

    Empedocles "discovered" that the heart is the organ of sense, and that all matter is comprised of four roots .
  • 300 BCE

    Herophilus of Chalcedon does one of the first public dissections of a cadaver in alexandria. he finds arteries are thicker than veins and they carry blood.
  • mid- 1200s

    Eminent Cairo describes the circulation of blood.
  • 1603

    Fabricius publishes documents containing the first drawings of vein valves.
  • 1553

    Michael Servetus suggests that blood flows through the lungs instead of the heart.
  • 1628

    William Harvey publishes EXERCITATIO ANATOMICA DE MOTU CORDIS ET SANGUINIS IN ANIMALIBUS (ANATOMICAL TREATISE ON THE MOVEMENT OF THE HEART AND BLOOD IN ANIMALS). he describes how blood is circulated throught the body and its pupmed by the heart.
  • 1658

    Jan Swammerdam is the first person to observe and describe red blood cells
  • 1661

    Marcello Malpighi describes the capillary system, the network of veins and arteries.
  • 1674

    Anton van Leeuwenhoek provides an even more accurate description of rbc's. he describes them as being 25000 times smaller than a grain of sand.
  • 1665

    Richard Lower performs the first blood transfusion between animals.
  • 1818

    British obstetrician and physiologist James Blundell perrform the first blood transfusion between humans.
  • 1874

    William Osler observes that bone marrow cells make up clots in blood vessels. (platelets)
  • 1901

    Karl Landsteiner publishes a document about his doscovery on the different types of blood types.
  • 1902

    Alfred von Decastello and Adriano Sturli identify the fouth blood type, AB.
  • 1907

    Dr. Ludvig Hektoen sugests checking patient blood type before giving a blood transfusion.
  • 1914

    Researchers find that mixxing in sodium citrate with blood will stop the blood from clotting.
  • 1915

    Dr. Richard Lewisohn finds that the optimum solution for sodium citrate in blood is just .2%
  • 1917

    Dr. Oswald Robertson stores type o blood to prepare for wounded soldiers coming back from battle. in doing so he created the first blood bank.
  • 1930

    Dr. Serge Yudin is the first to try using cadaver blood to help a human. he succesfully saved a young man using a 60 year olds dead body.
  • 1935

    Mayo Clinic in Rochester, MN organizes a transfusion service for hospitals.
  • 1936

    Federico Duran-Jorda begins collecting blood and refridgerating it so that he can transport it to soldiers in need during the spanish civil war
  • 1939-1940

    Drs. Karl Landsteiner and Alexander Wiener discover there is another blood group. they discover the rh blood group
  • 1940

    Edwin Cohn discovers a way of creating a durable substitute for plasma by seperating out its different proteins
  • 1941

    the american red cross agrees to create a nation wide blood donor service for the war and collect 13 million samples over the course of the war
  • 1948

    Dr. Carl W. Walter develops a plastic bag to hold blood safer and less likely to be contaminated.
  • 1959

    Dr. Max Perutz is able to discover the structure of hemoglobin using x rays
  • 1965

    Dr. Judith Pool discovers that plasma that is frozen and thawed slowly has a higher factor for clotting blood.
  • late 1960s

    Drs. Kenneth M. Brinkhous and Edward Shanbrom create a highly concentrated form of factor VIII. they create a powdered plasma with this that is 100 times better than any other.
  • 1971

    Dr. Baruch Blumberg discovers a material on hepatitis B that creates antibodies. this led to the creation of a test to identify hepatitis B.
  • 1981

    the first case of GRID (Gay-related Immunodeficiency Disease) is reported.(later called aids)
  • 1982

    Dr. Bruce Evatt suspects that patients with GRID may have the disease becasue it is blood borne.
  • 1983

    Researchers isolate the virus that causes aids and label it LAV (lymphadenopathy-associated virus).
  • 1984

    Dr. Robert Gallo finds the actual virus that causes aids called HTLV III (human T-cell lymphotropic virus).