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Christopher Columbus sails the Atlantice Ocean trying to find a western route to india. He later finds the West Indies.
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The Spanish brought slaves from Africa to Cuba for harsh labor.
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In Mexico, Cortez conqueres the Aztecs with 400 conquistadors and the help of some local tribes who disliked the Aztecs.
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In Peru, Pizarro conquers the incas with 169 soldiers and with some help of some native allies.
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The English colonize Jamestown. First English Colony
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Pilgrims colonize Plymouth. First New England settlement.
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French sign Peace Treaty with English. Ending the French and India War.