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The Soviet Union launched a dog into orbit first.
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Explorer 1
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pilot Alan Shepard
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astronaut John H. Glenn
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First onboard computer.
First docking of crewed and uncrewed spacecraft (Gemini VIII with Agena)
First propulsion maneuver with docked Agena (Gemini X) -
cosmonaut Alexei Leonov
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astronaut Edward White
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Apollo 1 - a fire erupted and rapidly asphyxiated all three astronauts.
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Yuri Alekseyevich Gagarin
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Apollo 7 - the first three-person American crew to launch to space.
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Apollo 11 -perform a crewed lunar landing and return to Earth.