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Christopher Columbus (d.1506) is born as is Amerigo Vespucci (d.1512), explorers.
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Nicolas Copernicus (1473-1543) born.
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Ferdinend Magellan famously completes the first circumnavigaton of the globe.
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Newton concentrated and sustained interest in alchemy.
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The Danzig astronomer Johannes Hevelius describes his instruments and provides one of the most extensive catalogues of the period.
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Edmond Halley provides a mathematical eq uation for finding the focal lengths of lenses of all shapes.
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Publication of the first textbook on the calculus by the Marquis de L'Hopital (1661-1704)
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Gottfied Wilhelm von Leibniz organizes and establishes the Berlin Academy of Science.
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Newton publisbes second English edition of Opticks with eight queries.
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newton's observiations upon the prophecies is published (london); some eleven printings follow.