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Christopher Columbus first makes contact with the native people. He calls them Indians because he thinks he has landed in the East Indies
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Pocahontas marries Englishman John Rolfe
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The beginning of the French and Indian War between France and Great Britain. Indian tribes were involved on both sides. The war ended in 1763.
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The Cherokee are forced to march from North Carolina to Oklahoma. Thousands of them die along the way in what will be known as the Trail of Tears.
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The Homestead Act is passed by the U.S. government opening Indian land in the Midwest to settlers
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- George Custer and the U.S. Army is soundly defeated at the Battle of Little Big Horn by Native Americans led by Sitting Bull.
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Charles Curtis becomes the first Native American U.S. Senator. He would later become vice president of the United States.
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Native American Indians are declared citizens of the United States.
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Chief Pontiac of the Ottawa led a rebellion against the British in the Ohio River Valley.