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An organization compensating settlers for losses resulting from Indian raids was created by Indian Commissioner Sir William Johnson.
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A troop of 50 armed men entered the Workhouse at Lancaster, Pennsylvania, and hacked to death the only 14 surviving Conestoga Indians (the rest of the tribe being similarly dispensed with 13 days earlier).
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Over four fifths (4/5) of the Arikara died of smallpox, measles, and etc.
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Forced to labor in the mission fields and to worship according to the misssionaries' teachings, the Indians at San Diego rebelled against the Spanish, burning every building, and killing most of the inhabitants, including the mission's head priest. Thanks to a Spanish sharpshooter, the Indians were finally driven off and the Spanish retained control of their outpost.
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The Continental Congress resolved that it was "highly expedient to engage Indians in service of the United Colonies,"
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The Cherokee Indians attacked a settlement in western North Carolina. Militia forces retaliated by destroying a nearby Cherokee village.
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Smallpox wiped out more than half of the Piegan Blackfeet.
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Captain David William and about 90 volunteer militiamen slaughtered 62 adults and 34 children of the neutral, pacifist, and Christian Deleware people at Gnadenhutten, Ohio in retaliation for raids by other Indian tribes.
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The Presidio, overlooking San Francisco, was erected by the Spanish to subdue Indians interfering with mail transmissions along El Camino Real.
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The Northwest Ordinance was enacted, stating "the utmost good faith shall always be observed toward the Indians... in their property, rights, and liberty they shall never be disturbed."
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First federal treaty enacted with the Deleware Indians.
